Two women in the last twenty years, plus Surya Bonaly attempting a quad, so three adult women in the last thirty. That's not exactly convincing evidence that adult women are physiologically capable of landing quads regularly and routinely like men can.
I don't know whether you had an access to the ice skating gear for the last 20 years, but boy, had the skates changed. Had the blades changed. The skates say, Miete, Medvedeva and some others use weight close to nothing. The good ol' shit I was using 30 years ago felt like 2kg each.
The technique of hte skaters who land the multiple quads (Chen, Jin, Hanuy, Uno, Kagiyama, Grassl, Zhou, Trusova, Valieva, Scherbakova....) is different than what we used to see in the past (Stojko, Yagudin, PLuschenko, Goebel, Joubert....) - in the last it was about jumping high and rotating the usual speed. Now it's all about rotating fast, not necessarily jumping high.
So the equipment had changed, the technique had changed.
I think the reason most of the ladies are not attempting the quads is well, mental/not wanting to be injured/no real point to attempt rules-wise (being forbidden in the SP).
And last, but not least, assume no one questions Duhamel being clean, yet she beautifully landed the quad throws.
The ladies can do them. Whether it's worth it - another question. Whether their coaches can teach them the right technique - another question .