Dunno if her thyroid is underactive. She's the biggest person in our family, but that's not saying anything since as you all know, the rest of my family are underweight sticks. She's very average in terms of weight. It's probably nothing major, but I'll suggest it.
She has noticed that her skin gets worse around her period, so it's at least partly hormonal, but pimples are still there at all times. IMO she might as well go on BC and see if that helps, she also suffers from pretty bad cramps so that might be a positive effect too.
I remember she was telling me about it several months ago and I looked it up on Wikipedia, and said that anything that "alters DNA transcription" is a bad thing in my eyes. Then again we kill cells at work with stuff that prevents cell division on a genetic level so I may be biased.